Advertisement
Results 1 to 2 of 2

Antidepressant Paroxetine For Hot Flashes

Prescription Medications and OTC Drugs - Medication Issues: Antidepressant Gets FDA OK for Hot Flashes Medpage Today June 28, 2013 The FDA has approved paroxetine* (Brisdelle), a selective ...

 

  1. #1
    Join Date
    Aug 2005
    Location
    Always In The Sunshine
    Posts
    8,272

    Post Antidepressant Paroxetine For Hot Flashes

    Antidepressant Gets FDA OK for Hot Flashes
    Medpage Today
    June 28, 2013


    The FDA has approved paroxetine* (Brisdelle), a selective serotonin reuptake inhibitor (SSRI), to treat moderate to severe hot flashes associated with menopause.

    "Today's approval provides women with the first FDA-approved, nonhormonal therapeutic option to help ease the hot flashes that are so common in menopause," said Hylton Joffe, MD, director of the division of bone, reproductive, and urologic products at the FDA's Center for Drug Evaluation and Research.

    The safety and efficacy of the drug in this condition was established in two randomized, double-blind, controlled studies in 1,175 postmenopausal women with moderate to severe hot flashes.

    Women in the study had a minimum of seven to eight hot flashes per day or 50 to 60 per week.

    Treatment lasted 12 weeks in one study and 24 weeks in another, and both trials showed that paroxetine reduced hot flashes better than placebo.

    The most common side effects with the drug included headache, fatigue, and nausea or vomiting,

    The dosage approved for use in hot flashes (7.5 mg) is far lower than that used in conditions such as major depressive disorder, obsessive-compulsive disorder, panic disorder, and generalized anxiety disorder.

    Still, the medication will contain a boxed warning about suicidality given that this side effect is included in the label for the drug when it is used in higher doses in the other conditions.

    Additional warnings that will be included in the label will note a possible reduction in the efficacy of tamoxifen if both medications are used together, an increased risk of bleeding, and a risk of developing serotonin syndrome symptoms of which include confusion, rapid heart rate, and high blood pressure.

    The drug will be marketed by Noven Therapeutics of Miami.

    *paroxetine is also known as Paxil, Paxil CR, Pexeva

  2. Advertisement
  3. #2

    Re: Antidepressant Paroxetine For Hot Flashes

    I have a family member who finds this drug the best one for her depression....maybe it will take care of menopausal symptoms too....interesting.

Similar Threads

  1. Nonhormonal treatment for hot flashes approved by FDA
    By David Baxter in forum Hormones and Mental Health
    Replies: 1
    Last Post: March 10th, 2011, 04:56 PM
  2. Antidepressants Emerge as Coolant for Hot Flashes
    By David Baxter in forum Hormones and Mental Health
    Replies: 0
    Last Post: October 15th, 2007, 09:02 AM
  3. Anxiety Worsens Hot Flashes
    By David Baxter in forum Hormones and Mental Health
    Replies: 3
    Last Post: October 11th, 2006, 10:45 AM
  4. Doctors' group says antidepressants safe for teens
    By David Baxter in forum Medications and Suicide Risk
    Replies: 23
    Last Post: September 22nd, 2005, 09:41 AM
  5. Antidepressant Medications for Children
    By David Baxter in forum Medications and Suicide Risk
    Replies: 1
    Last Post: May 24th, 2004, 09:05 AM

Bookmarks

Bookmarks

Posting Permissions

  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts
  •  

PsychLinks is not responsible for the content
of posts or comments by forum members.
This website is certified by Health On the Net Foundation. Click to verify. Psychlinks complies with the HONcode standards
for health trustworthy information: verify here.


Additional Forum Web Design by PsychLinks and Wilder Tweedale Web Design
© All rights reserved.

HOSTING BY




PSYCHLINKS RECOMMENDS