Hi. I'm new to the forum, so hope this is the right place to ask this? I have Major (unipolar) Depression & have been on 300mgm. of Effexor for 5 years with good results, until the past 6 months when the effectiveness of Effexor has decreased & I've foung myself fighting the "black edges" more often again. My doctor has suggested that I augment the Effexor with 25 mg. of Seroquel once a day. This surprised me, since Seroquel is an atypical anti-psychotic. After checking side-effects of Seoquel I am extremely reluctant to take it, particularly since there is a Health Canada warning on the drug that it can cause diabetes, along with several other rather serious side-effects. So my questions are:
- Does anyone had any luck combining Effexor with any other drug or agent for good results in Augmentation?
- Is anyone on a dose of Effexor XR that is higher than 300mg per day?
- Any comments re experiences with Seroquel?
Thanks so much!