GLP-1s for obesity include Zepbound (tirzepatide) and Wegovy (semaglutide). Before I started on tirzepatide (a compounded version of Zepbound), I did not know what to think about pros vs cons. But now that I am on them, I agree with the comments below since the "food noise" is a fraction of what I used to endure. So I am doing much better mentally and physically, with no lingering side effects.
Millions of people are now on GLP-1s, and their lab results show they will live longer as a result. In the US, the most affordable option for Zepbound is getting tirzepatide at Brello.
From a doctor:
Research has shown the majority of overweight people have a GLP-1 peptide hormone deficiency. How do we treat hormone deficiencies in healthcare? Keep in mind, after the desired weight loss is achieved, a lower maintenance dose is needed to cover this deficiency. Find the lowest dose that helps maintain the weight loss, which is different with everyone.
Peptide hormones are no longer expensive to make. Greed and corporate control make what should be relatively simple medical healthcare option impossible to start or unaffordable to maintain, for the majority. Keeping them insatiably hungry, fat, and sick is essential for the bottomline.
Contrary to (special interest) programmed fear-based beliefs, compounded versions of GLP-1 meds simply represent a better mouse trap.Turning the unaffordable into affordable is a good thing in medicine. Accessibility saves lives and significantly improves quality of life, for those who can find this access point.
From a nurse:
I think there are several things that can be gained from the use of GLP-1s. Just like everything else, this is not a one size fits all solution. I think the true beauty lies in preventing patients from becoming insulin dependent. Sure most people gain the weight back after discounting medications but the same is true of exercise and a healthy diet.
Patients who have struggled to lose weight gain a huge boost to their confidence when they see it start to fall off with these drugs. A good number feel better enough both physically and mentally to put into place the lifestyle changes that will help them keep the weight off. The other thing I find fascinating about these drugs is the reduction in food noise and reduction in appetitite. My hope is that the research will allow us to further narrow down the pharmacology so that maybe in the future a true appetite suppressant medication could be developed.
From what I've seen in practice is that patients are not only satiated sooner and experience less food noise, but they do not crave sweets or carbs in particular. I obviously cannot produce reliable numbers to prove what I've seen in patients but I've definitely noticed and am hopeful that enough people benefit to make these meds still worthwhile. As for the long term effects, I would still wager on reducing the chances of death due to heart disease or diabetes for myself.
Source: Comments at
www.medpagetoday.com
Millions of people are now on GLP-1s, and their lab results show they will live longer as a result. In the US, the most affordable option for Zepbound is getting tirzepatide at Brello.
From a doctor:
Research has shown the majority of overweight people have a GLP-1 peptide hormone deficiency. How do we treat hormone deficiencies in healthcare? Keep in mind, after the desired weight loss is achieved, a lower maintenance dose is needed to cover this deficiency. Find the lowest dose that helps maintain the weight loss, which is different with everyone.
Peptide hormones are no longer expensive to make. Greed and corporate control make what should be relatively simple medical healthcare option impossible to start or unaffordable to maintain, for the majority. Keeping them insatiably hungry, fat, and sick is essential for the bottomline.
Contrary to (special interest) programmed fear-based beliefs, compounded versions of GLP-1 meds simply represent a better mouse trap.Turning the unaffordable into affordable is a good thing in medicine. Accessibility saves lives and significantly improves quality of life, for those who can find this access point.
From a nurse:
I think there are several things that can be gained from the use of GLP-1s. Just like everything else, this is not a one size fits all solution. I think the true beauty lies in preventing patients from becoming insulin dependent. Sure most people gain the weight back after discounting medications but the same is true of exercise and a healthy diet.
Patients who have struggled to lose weight gain a huge boost to their confidence when they see it start to fall off with these drugs. A good number feel better enough both physically and mentally to put into place the lifestyle changes that will help them keep the weight off. The other thing I find fascinating about these drugs is the reduction in food noise and reduction in appetitite. My hope is that the research will allow us to further narrow down the pharmacology so that maybe in the future a true appetite suppressant medication could be developed.
From what I've seen in practice is that patients are not only satiated sooner and experience less food noise, but they do not crave sweets or carbs in particular. I obviously cannot produce reliable numbers to prove what I've seen in patients but I've definitely noticed and am hopeful that enough people benefit to make these meds still worthwhile. As for the long term effects, I would still wager on reducing the chances of death due to heart disease or diabetes for myself.
Source: Comments at
Opinion | I No Longer Think GLP-1s Are the Answer
The drugs 'work' but may be working against us long-term
www.medpagetoday.com
