From what I gather and I stand to be corrected, generalized anxiety disorder (GAD) is not caused by having low self esteem however having low self esteem may have an effect on an existing anxiety disorder.
For a better understand of what generalized anxiety disorder is you may want to take a look at this link: Understanding Anxiety Disorders.
For great information on Self Esteem you may want to check out this link: Better Self-Esteem
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