More threads by David Baxter PhD

David Baxter PhD

Late Founder
Borderline personality disorder has 'distinct neuropathology'
By Andrew Czyzewski
29 October 2007
J Clin Psychiatry 2007; 68: 1533-1539

Borderline personality disorder (BPD) is a distinct condition with a unique symptom profile that differentiates it from other affective disorders, confirm the results of study.

Scott Wilson, from the New York State Psychiatric Institute, in New York, USA, and colleagues also found that patients with bipolar II disorder who have co-existing BPD might have more severe symptoms than patients with bipolar II disorder alone.

BPD and bipolar affective disorder frequently co-occur and there can be a degree of overlap in symptoms, leading some investigators to suggest that BPD exists along a spectrum of affective disorders, the researchers explain.

Some have even suggested that BPD may be an ultra-rapid cycling form of bipolar II disorder, they add.

To explore this relationship, the researchers recruited 173 patients with either major depressive disorder (MDD) or bipolar II disorder and further divided them based on the presence or absence of coexisting BPD.

Patients were interviewed and assessed for depression, impulsiveness, hostility, and guilt using various scales.

Wilson et al found that patients who had BPD scored significantly higher on both the Buss-Durkee Hostility Inventory and the Barratt Impulsiveness Scale than the other patients.

Patients with bipolar II and BPD had the highest average level of impulsivity, scoring 63.6, followed by patients with MDD and BPD, who scored 58.8. The lowest scores were for bipolar II disorder and MDD alone, scoring 29.4 and 26.0, respectively.

Noting that this finding hints at a complex relationship between the syndromes, the researchers looked in more detail at impulsiveness subscales.

They found that bipolar II disorder was uniquely associated with increasing levels of attention impulsiveness. In contrast, BPD was uniquely associated with an increase in non-planning impulsiveness.

This finding, say the researchers, supports the theory that different facets of impulsiveness are associated with each diagnostic syndrome and that there may be a distinct neuropathology underlying each diagnosis.

"This finding not only suggests a degree of independence between the diagnoses but also suggests that patients with this combination of disorders could have particularly high risk for self-destructive or damaging behavior such as suicide attempts and self-injury," the team concludes.

Journal
 

Similar threads

There are many paradoxes associated with BPD. A paradox is something that is self-contradictory. Those who have BPD have a tendency to experience something called the empathy paradox. The empathy paradox, for individuals with BPD, is that they are good at reading emotions in others due to paying extra attention to what’s going on in their environment and the people in it, but this information gets distorted along the way causing the individual with BPD to misinterpret those emotions as...
Replies
1
Views
527
Understanding the Relationship Cycle in Borderline Personality Disorder by Hope Gillette, Psych Central Dec 14, 2021 If you’ve been in a relationship with someone with borderline personality disorder (BPD), you may know things can get emotional and intense at times. A BPD relationship cycle often consists of some emotional highs and lows that may leave you confused and frustrated. You might also see your partner experience unexpected bouts of anger, anxiety, or depression. They may love...
Replies
0
Views
2K
NIMH Livestream Event on Borderline Personality Disorder Date/Time: Friday, May 21, 2021, 1:30–2:00 PM ET Location: Virtual In recognition of National Borderline Personality Disorder Awareness Month in May, NIMH is hosting a livestream event on Friday, May 21, 2021, from 1:30 – 2:00 p.m. ET. Borderline personality disorder is an illness marked by an ongoing pattern of varying moods, self-image, and behavior. These symptoms often result in impulsive actions...
Replies
0
Views
2K
How to Deal With a Person With Borderline Personality Disorder BY Nancy Carbone, Mental Health Matters September 8, 2017 Individuals with borderline personality disorder (BPD)are easily triggered into feeling bad about themselves and will often misinterpret others as putting them down or rejecting them, even though this may not be true. They often react, to ward off these feelings by projecting them onto others, so others are bad, uncaring or mean. It is very difficult for...
Replies
0
Views
18K
Yes unfortunately it often seems to be used as a way of denying help to a whole group of people who really need it and basically gas-lighting them and further traumatising them. That's how it is here anyway, with resources severely limited (and I know this diagnosis is definitely not the only one not getting adequate help, but maybe the main one where people get shamed and ignored for something that's already causing them huge distress, by the people who they have been told to turn to for...
Replies
2
Views
4K
Top