CBT vs Risperidone for Treatment-Resistant OCD

[Retired]

Augmentation With Cognitive Behavioural Therapy Has Superior Efficacy to Augmentation With Risperidone for Treating Adults With Treatment-Resistant OCD
Medscape Medical News
Evid Based Ment Health. 2014;17(2):58-59.
July 1, 2014

Excerpt:

This first large-scale (100 patients) comparison of the two augmentation strategies yielded far superior efficacy in symptom reduction, remission and other metrics for EX/RP than for risperidone.

Risperidone was only slightly (but not significantly) more effective than placebo.

Adverse effects of 12-week SRI treatment were also observed in overall 37% of patients at baseline, which is more than expected.

Complete article attached