Zoloft Dosage is 300mg.

[Crazy Cat]

After a year of going on and off countless antidepressants, I find myself back where I started; on Zoloft. However now I'm taking 300mg instead of 200mg.

According to the Zoloft website, 200mg is the highest they recommend. I'm wondering if I can jump to 400mg?

In the last 10 years I have been on no less than 15 antidepressants that either worked for a while and stopped working or just didn't work at all. So far the Zoloft seems to be the one but I definitely need a boost. I've tried the add-to drug Abilify already. Didn't help.

 

[Retired]

However now I'm taking 300mg instead of 200mg.

According to the Zoloft website, 200mg is the highest they recommend. I'm wondering if I can jump to 400mg?

There may be a rational clinical justification for increasing the dose beyond the manufacturer's recommendation in the Product monograph, and you need to discuss this with the prescribing doctor to ask what the rationale is.

There may be recent clinical studies that report the use of higher doses for certain situations.

You have the right to ask to understand the reason for any therapy you receive, and you have the option to accept it or to refuse it if you have a strong reason.

Decisions should be based on sound medical knowledge and not on internet based claims and biases.

The most reliable document used as a reference for any medication is the manufacturer's product monograph, often available as a pdf download from the manufacturer's website. In the U.S. and In Canada (the latter will download a Pfizer pdf monograph from Health Canada Archives.

Speak to your pharmacist and if you are still unsure, ask for a second opinion from a different doctor or ask for a consultation with a clinical pharmacologist, as specialist in medications.

What is the diagnosis being treated and has the prescribing doctor provided any insights or rationale for this higher dosage?